\[ \left (a+x^{22}-y(x)^2\right ) y'(x)+x y(x) y'(x)^2-x y(x)=0 \] ✗ Mathematica : cpu = 63.1457 (sec), leaf count = 0 , could not solve
DSolve[-(x*y[x]) + (a + x^22 - y[x]^2)*Derivative[1][y][x] + x*y[x]*Derivative[1][y][x]^2 == 0, y[x], x]
✗ Maple : cpu = 0. (sec), leaf count = 0 , could not solve
dsolve(x*y(x)*diff(y(x),x)^2+(x^22-y(x)^2+a)*diff(y(x),x)-x*y(x) = 0,y(x))